Puas yog Rotovap Distillation?

Yog, arotovap ua, luv luv rau rotational evaporator, yog ib hom khoom siv kho kom zoo uas feem ntau siv hauv qhov chaw tshawb fawb kom ua tau zoo thiab maj mam tshem tawm cov kuab tshuaj los ntawm kev ntsuam xyuas los ntawm dissipation. Nws yog dav siv nyob rau hauv chemistry, natural chemistry, thiab kws tshuaj ntsuam xyuas rau cov kev siv sib txawv xws li kev sib koom ua ke, kev ua kom zoo ntawm cov tebchaw, thiab kev rov ua kom rov zoo.

 

Txoj cai tseem ceeb tom qab lub rotovap suav nrog kev ua kom sov qhov ntsuas hauv qab lub tshuab nqus tsev thaum tig nws kom nce thaj tsam saum npoo uncovered rau lub tshuab nqus tsev. Qhov no ua kom nrawm nrawm, tso cai rau cov kuab tshuaj tsis ruaj khov kom vaporize ntawm qhov kub qis dua hauv qab huab cua hnyav. Lub vapor yog nyob rau ntawm qhov chaw condensed rov qab mus rau hauv cov kua theem thiab sau ntawm nws tus kheej, tshem tawm tom qab lub xav compound los yog tshuaj nyob rau hauv ib tug concentrated daim ntawv.

 

Rotovaps yog qhov tshwj xeeb tshaj yog muaj txiaj ntsig rau kev saib xyuas cov cua sov-rhiab qhov sib xyaw uas tuaj yeem tawg ntawm qhov kub siab dua, vim tias qhov hnyav poob qis ua rau lub bubbling point ntawm lub dissolvable, txo lub sij hawm ntawm sov debasement. Tsis tas li ntawd, kev sib tw pivoting txav ua qhov sib txawv kom tsis txhob muaj kev sib tsoo lossis tawg ntawm qhov kev sim, lav kom muaj txiaj ntsig ntau dua thiab kev tswj hwm zoo tshaj ntawm kev npaj.

 

Nyob rau hauv lub cheeb tsam ntawm cov cuab yeej kuaj, Rotovap sawv tawm raws li ntau yam cuab yeej siv dav siv rau ntau yam kev siv, tshwj xeeb tshaj yog nyob rau hauv chemistry. Nrog nws cov qauv tsim thiab kev ua haujlwm zoo, Rotovap muaj txoj hauv kev zoo rau kev sib cais cov kuab tshuaj los ntawm cov tebchaw los ntawm evaporation. Nyob rau hauv tsab xov xwm no, peb delve rau hauv intricacies ntawm Rotovap, tshawb txog nws cov hauv paus ntsiab lus, kev siv, qhov zoo, thiab kev saib xyuas kev nyab xeeb.

 

Nkag siab txog Rotovap

CovRotovap, luv luv rau Rotary Evaporator, yog lub tshuab kuaj kab mob siv rau kev tshem tawm cov kuab tshuaj los ntawm cov qauv los ntawm evaporation. Nws muaj lub rotating round-bottom flask, feem ntau yog ua los ntawm iav, txuas nrog lub tshuab nqus tsev twj thiab lub condenser. Lub raj mis yog muab tso rau hauv ib lub da dej rhuab, tso cai rau kev tswj cua sov ntawm cov qauv.

Lub rotary evaporator, feem ntau hu ua rotovap, yog cov cuab yeej kuaj siv rau kev tshem tawm cov kuab tshuaj los ntawm cov qauv los ntawm evaporation. Nws muaj ntau yam tseem ceeb:

Kev ua haujlwm ntawm rotary evaporator feem ntau suav nrog cov kauj ruam hauv qab no:

Lub hauv paus ntsiab lus qab Rotovap

Kev ua haujlwm ntawm lubRotovaptso siab rau lub hauv paus ntsiab lus ntawm kev txo siab thiab cua sov kom pab txhawb evaporation. Los ntawm kev txo qis hauv lub zog siv lub tshuab nqus tsev twj, qhov kub ntawm cov kuab tshuaj txo qis, ua kom cov evaporation tshwm sim ntawm qhov kub qis dua li atmospheric siab. Kev sib hloov ntawm lub raj mis nce qhov chaw ntawm cov qauv raug tshav kub, ntxiv dag zog rau cov txheej txheem evaporation.

Daim ntawv thov ntawm Rotovap nyob rau hauv Laboratory Chaw

Lub versatility ntawm Rotovap ua rau nws invaluable nyob rau hauv ib tug ntau yam ntawm kev sim daim ntaub ntawv. Nws yog feem ntau siv rau cov kuab tshuaj tshem tawm, concentration ntawm kev daws, thiab purification ntawm cov tebchaw. Tsis tas li ntawd, lubRotovappom kev siv hluav taws xob hauv cov txheej txheem xws li molecular distillation, qhov chaw nqus tsev siab yog tsim nyog rau kev sib cais ntawm cov khoom tsis haum.

Muab piv Rotovap nrog Cov Txheej Txheem Tso Cai Tso Cai

Thaum Rotovap qhia qhov zoo sib xws nrog cov txheej txheem distillation ib txwm, xws li fractional distillation thiab yooj yim distillation, nws muaj qhov zoo sib xws ntawm kev ua tau zoo thiab qhov tseeb. Tsis zoo li cov kev teeb tsa ib txwm siv uas tso siab rau cov cua sov rau evaporation nkaus xwb, Rotovap kev sib xyaw ua ke ntawm cov cua sov thiab txo qhov siab tso cai rau kom ceev evaporation tus nqi thiab ua haujlwm qis dua. Cov txheej txheem no maj mam txo qhov kev pheej hmoo ntawm thermal degradation los yog poob ntawm volatile tebchaw, ua rau nws tshwj xeeb tshaj yog muaj txiaj ntsig zoo rau cov khoom kub-rhiab heev.

Qhov zoo ntawm kev siv Rotovap

Rotovap muaj ntau qhov zoo dua li cov txheej txheem distillation. Nws lub peev xwm los ua haujlwm nyob rau hauv lub tshuab nqus tsev ua rau qis zog siv thiab txo lub sijhawm ua haujlwm. Tsis tas li ntawd, qhov kev sib hloov ua kom muaj cua sov zoo sib xws thiab cov kuab tshuaj evaporation zoo, ua rau muaj txiaj ntsig ntau dua thiab txhim kho purity ntawm cov khoom kawg. Tsis tas li ntawd, qhov loj me ntawm Rotovap ua rau nws zoo tagnrho rau kev siv hauv qhov chaw sim me me uas qhov chaw yuav raug txwv.

Kev txwv thiab kev sib tw

Txawm hais tias nws cov txiaj ntsig zoo heev, Rotovap tsis yog tsis muaj kev txwv thiab kev sib tw. Ib qho kev txwv tseem ceeb yog nws qhov tsim nyog feem ntau rau kev sim me me vim nws qhov peev xwm tsawg. Cov txheej txheem tsim khoom loj tuaj yeem xav tau lwm cov khoom siv uas muaj peev xwm tuav tau ntau dua. Tsis tas li ntawd, qee cov qauv piv txwv lossis cov kuab tshuaj sib xyaw ua ke tuaj yeem ua rau muaj teeb meem ntawm kev ua haujlwm ntawm evaporation lossis kev sib raug zoo nrog cov ntaub ntawv ntawm kev tsim kho.

Kev txiav txim siab txog kev nyab xeeb thaum siv Rotovap

Kev nyab xeeb yog qhov tseem ceeb thaum ua haujlwm ntawm cov khoom siv hauv chav kuaj, suav nrog Rotovap. Kev cob qhia kom raug thiab kev saib xyuas yog qhov tseem ceeb los xyuas kom muaj kev nyab xeeb ntawm cov tshuaj thiab kev ua haujlwm ntawm cov khoom siv. Nws yog ib qho tsim nyog yuav tsum ua raws li cov chaw tsim khoom cov lus qhia thiab cov txheej txheem kev khiav hauj lwm kom txo tau cov kev pheej hmoo xws li tshuaj lom neeg raug mob, implosion txaus ntshai, thiab overheating. Tsis tas li ntawd, kev siv cov cuab yeej tiv thaiv tus kheej tsim nyog, xws li tsom iav thiab hnab looj tes, tau pom zoo txhua lub sijhawm.

Xaus

Hauv kev xaus, lubRotovapua pov thawj tias yog ib qho cuab tam muaj txiaj ntsig hauv chav kuaj, muab cov kuab tshuaj tshem tawm tau zoo thiab muaj peev xwm concentration. Nws cov qauv tsim tshwj xeeb thiab cov qauv kev ua haujlwm ua rau nws zoo haum rau ntau yam kev siv, los ntawm kev niaj hnub hnyav evaporation mus rau cov txheej txheem tshwj xeeb xws li molecular distillation. Txawm hais tias nws yuav muaj kev txwv ntawm cov nplai thiab kev sib raug zoo, nws qhov zoo ntawm kev ua tau zoo, kev ua tau zoo, thiab qhov chaw txuag tsim ua rau nws xaiv rau ntau tus kws tshawb fawb thiab cov kws tshawb fawb.

Cov ntaub ntawv

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"Rotary Evaporator." Chemistry LibreTexts. https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Supplemental_Modules_(Organic_Chemistry)/Laboratory_Techniques

"Rotary Evaporation." Royal Society of Chemistry. https://www.rsc.org/learn-chemistry/resource/res00001442/rotary-evaporation?cmpid=CMP00001442