Lub tshuab nqus nqus khov ua kom tsis muaj protein ruaj khov?

Protein ruaj khov yog qhov tseem ceeb hauv kev lag luam, los ntawm kws tshuaj, los ntawm kws tshuaj rau khoom noj. TusDeep Kom Qhuav Tshuab Ziab Khaub Ncawstau tawm los ua cov cuab yeej muaj zog rau khaws cov qauv protein thiab tswj lawv cov haujlwm. Cov lus sau no rho tawm kev sib raug zoo sib sib zog nqus kom qhuav thiab ua kom muaj zog, piv cov txiaj ntsig, thiab cov txheej txheem kom tsim nyog.

 

 

Peb muabDeep Kom Qhuav Tshuab Ziab Khaub Ncaws, thov saib mus rau lub vev xaib txuas ntxiv no kom cov ncauj lus kom ntxaws thiab cov ntaub ntawv.

Khoom:https://www.achievechn.com/freeer-dryer/pilot-freeze-dryer-html

 

Lub tshuab nqus kom khov lub tshuab ua haujlwm kom nruj tus txheej txheem los khaws cov protein hauv lawv lub xeev haiv neeg. Hom qauv no, hu ua Lyophilization, cuam tshuam nrog kev hle cov dej los ntawm cov qauv protein khov hauv lub tshuab nqus tsev. Cov txheej txheem tshwm sim hauv ntau theem:

● Tsoo: khov khov: nrawm ntawm cov protein daws los tsim cov dej khov Thawj qhuav: Sublimation ntawm dej khov ncaj qha rau hauv vapor Alflection Thib Ob: Tshem tawm cov dej noo seem

Thaum cov theem no, tshuab ziab khaub ncaws khov ua kom khov kho cov protein hauv lub xeev ruaj khov, kev tiv thaiv molecular thiab tiv thaiv denaturation. Qhov tsis muaj dej ua kua dej inhibits ntau yam kev hloov pauv, zoo "txhav" cov protein nyob hauv lawv cov kev sib koom ua ke.

Qhov kub qis siv hauv tob khov kom qhuav kuj ua lub luag haujlwm tseem ceeb hauv protein ruaj khov. Los ntawm kev ua haujlwm zoo hauv qab no cov ntxaij hloov pauv, cov txheej txheem cuam tshuam ntau dua kev pheej hmoo ntawm kev sib cav sib ceg thiab tshuaj lom neeg saib xyuas.

Tsis tas li ntawd, lub tshuab nqus tsev ib puag ncig hauv lub tshuab nqus khov kom tshem tawm oxygen, uas tuaj yeem ua rau oxidative kev puas tsuaj rau cov protein. Qhov kev mob anaerobic no pab khaws cov amino acid seem, xws li cysteine ​​thiab methionine, uas yog nquag mus rau oxidation.

 

Thaum nws los khaws cia protein ruaj khov, lub tshuab ziab khaub ncaws nqus kom muaj ntau txoj kev kom qhuav. Cia peb kuaj seb nws muab piv rau lwm cov kev txawj:

Cov Txau Kom Qhuav

Thaum cov tshuaj pleev kom qhuav yog txoj kev nrawm nrawm thiab muaj txiaj ntsig zoo, nws nthuav tawm cov protein rau qhov kub, uas tuaj yeem ua rau muaj kev cuam tshuam thiab ploj ntawm kev ua haujlwm biological. Hauv kev sib piv, qhov tob tob khov ua haujlwm ntawm cov cua kub qis, txo cov cua sov ntawm cov protein.

Cov kev tshawb fawb tau pom tias cov enzymes qhuav siv lub tshuab ziab khaub ncaws khov kho kom tau cov kev ua si ntau dua rau cov tshuaj tsuag. Piv txwv li, -galactosidase khaws cia los ntawm tob kom qhuav tswj tau ntau dua 90% ntawm nws qhov kev ua si thawj zaug, thaum cov tshuaj tsuag-qhuav khaws cia tsuas yog 60%.

Ack Huab cua kom qhuav

Cua kom qhuav, txawm yooj yim thiab pheej yig, tuaj yeem cuam tshuam rau cov protein ruaj khov. Lub caij nyoog raug rau kev mob zoo thaum lub sij hawm cua kom qhuav tuaj yeem ua rau oxidation thiab kev hloov pauv ntawm cov protein.

Kev tshawb fawb sib piv kev sib xyaw huab cua-qhuav thiab khov-qhuav cov qauv protein tau ua ntu zus hauv cov khoom khov kho khov kho hauv cov hnoos qeev kom qhuav. Piv txwv li, kev kawm txog collagen pom tias cov qauv khov-qhuav tswj xyuas lawv li triple-helix, thaum cua-qhuav kuaj cov qauv kev hloov pauv tseem ceeb.

Lub Tshuab Nqus Tsev Kom Qhuav

Lub tshuab nqus tsev qhuav muab qee qhov zoo dua cua kom qhuav, tab sis nws tseem poob qis ntawm cov protein kom muaj peev xwm tiv thaiv khov. Qhov tsis muaj ib tug tub rog khov hauv lub tshuab nqus tsev kom qhuav rau cov txheej txheem molecular lub sijhawm ua kom cov txheej txheem ua kom qhuav.

Cov kev ntsuas sib piv tau qhia tias cov protein qhuav siv lub tshuab nqus khov ua kom pom cov qauv kev sib sau ua ke thiab cov qauv ntau dua piv rau cov qauv ziab. Qhov no tshwj xeeb tshaj yog pom tseeb nyob rau hauv cov ntaub ntawv ntawm loj, cov protein ntau xws li tshuaj tiv thaiv.

 

Thaum lub tshuab nqus tsev khov khov kho kom haum rau cov txheej txheem protein kom zoo, ua kom cov txheej txheem ua kom tau yooj yim ntxiv, tshwj xeeb tshaj yog rau cov tshuaj tiv thaiv tsis txaus ntseeg. Ntawm no yog cov ntsiab lus tseem ceeb los xav txog:

Khov Kub Tus nqi ntawm cov protein uas khov tau khov kho tau lawv qhov ruaj khov thaum lub sijhawm ua kom qhuav. Qhov khov sai yog feem ntau ua rau cov dej khov nab kuab me, uas tuaj yeem pab txuag cov qauv protein. Txawm li cas los xij, cov nqi siab khov sai heev tuaj yeem ua rau muaj kev txwv tsis pub txias hauv qee cov protein. Rau feem ntau cov protein, ib txwm khov kom khov tus nqi (1-10 degree / min) hauv qhov ua kom khov khov kho. Tus nqi no tso cai rau kev tsim cov muaju dej khov me me tsis muaj kev pheej hmoo txias denaturation. Thawj qhuav qhuav Qhov kub thaum pib ua kom qhuav yuav tsum tau ua tib zoo tswj hwm lub xeev khov ntawm cov protein thaum tso cai rau cov sublimation txuag. Kev khiav hauj lwm dhau ze rau lub cev qhuav dej yuav ua rau cov kev hloov pauv thiab tsis muaj protein ntau. Feem ntau, tswj cov khoom kub 2-5}}}}} degree hauv qab no lub taub hau qhuav rau cov txiaj ntsig zoo tshaj plaws rau cov protein ruaj khov. Qhov ntsuas kub no ntau ua kom muaj kev tshem tawm dej nrawm thaum khaws cov protein cov qauv kev ncaj ncees.

Thib Ob Kom Qhuav Cov theem kawg ntawm kev nqus khov kom qhuav, hu ua cov kev ziab kom qhuav, tshem tawm cov qauv noo noo los ntawm cov tshuaj tiv thaiv protein. Qhov ntsuas kub thiab ntev ntawm theem no tuaj yeem cuam tshuam tau cov protein ruaj khov. Maj mam nce qhov kub thiab txias rau hauv lub tshuab ziab khaub ncaws me ntsis tso rau kom muaj cov dej noo ntau dua uas tsis muaj cov qauv muaj protein ntau. Ib txoj hauv kev yog los tsa qhov kub thiab txias hauv 5-10} degree nce ntxiv, nrog txhua kauj ruam kav ntev li ob peb teev. Ntxiv thiab Tsim Qhov sib ntxiv ntawm stabilizing cov neeg sawv cev rau cov tshuaj protein ua ntej kom qhuav-kom qhuav tuaj yeem txhim kho kev ruaj khov thaum lub sijhawm thiab tom qab khaws cia. Cov khoom ntxiv suav nrog: SUGARS (piv txwv li, Trealhalose, Sucrose): Ua raws li cov neeg ua tsis muaj qab hau, hloov cov roj molecules thiab kev tswj cov qauv protein Cov amino acids (piv txwv li, glycine, arginine): tiv thaiv kev sib sau ua ke thiab tiv thaiv kev hloov ntawm hom pH Surfactants (piv txwv li, polysorbate 80): txo cov protein adsorption rau cov chaw thiab tiv thaiv kev sib cais Ua kom zoo dua cov qauv tsim rau txhua cov protein tuaj yeem txhim kho nws qhov ruaj khov thaum ziab kom qhuav-kom qhuav thiab ntev cia.

TusDeep Kom Qhuav Tshuab Ziab Khaub Ncawssawv tawm raws li lub cuab yeej muaj zog rau kev tswj cov protein ruaj khov hla ntau yam kev siv. Nws lub peev xwm los khaws cov protein nyob hauv lawv cov haiv neeg hauv lub xeev, txuas nrog cov khoom muaj txiaj ntsig zoo rau kev lag luam tawm ntawm cov kws tshuaj rau cov khoom noj.

Raws li kev tshawb fawb txuas ntxiv ua ntej peb txoj kev nkag siab ntawm tus cwj pwm protein thaum lub sijhawm ua kom huv, peb tuaj yeem cia siab ntau dua rau cov txheej txheem kom tob tob kom tob tob. Qhov kev nce qib zuj zus yuav tsis ntseeg los txhim kho Biomolecules xws li kev txhim kho tshuaj, kev kuaj mob, thiab khoom noj ua haujlwm zoo.

Rau cov tuam txhab ua lag luam, cov kws ua lag luam siv tshuaj, thiab cov chaw tshawb xyuas tseem ceeb ntawm cov khoom lag luam zoo thiab tshawb fawb tshwm sim.

Puas yog koj tab tom nrhiav kom ua kom koj cov protein khaws cia? Ua tiav kev chemical muaj lub xeev-ntawm-kev ua yeeb yaj kiab av khov khov khov tshuab cov kev daws teeb meem rau koj cov kev xav tau. Nrog peb cov ntawv pov thawj EU CE, ISO9001 Kev Tswj Xyuas Kev Tswj Xyuas Zoo, thiab cov khoom siv tshwj xeeb, peb muab cov khoom siv tshwj xeeb thiab siv tau cov khoom siv tshwj xeeb. Tiv tauj peb ntawmsales@achievechem.comYog xav paub ntau ntxiv txog yuav ua li cas peb cov tshuab nqus kom khov khov lub tshuab ziab khaub ncaws tuaj yeem hloov kho koj cov protein kev tswj hwm.