Puas yog Rotovap Evaporate Dej?

yog, a rotary evaporator(rotovap) tuaj yeem siv rau evaporate dej, nrog rau lwm cov kuab tshuaj. Lub hauv paus ntsiab lus ntawm rotary evaporator yog ua raws li kev txo qis hauv lub kaw lus kaw, uas txo qis qhov kub ntawm cov kuab tshuaj, tso cai rau nws evaporate ntawm qhov kub thiab txias.

Dej muaj qhov kub kub kub ntawm atmospheric siab (100 degree lossis 212 degree F), tab sis nyob rau hauv qhov txo qis, nws qhov kub kub tuaj yeem qis dua. Los ntawm kev siv lub tshuab nqus tsev, lub siab nyob rau hauv lub evaporator teb yog txo, uas txo cov boiling point ntawm dej, ua rau nws evaporation ntawm kub hauv qab no 100 degree.

Yog li ntawd, lub evaporator teb tau zoo evaporate dej los ntawm cov kua sib tov, tso cai rau kom muaj zog thiab purification ntawm aqueous daws los yog rho tawm cov dej los ntawm cov qauv. Qhov no ua rau rotary evaporation ib tug ntau yam txheej txheem siv nyob rau hauv ntau yam xws li chemistry, biology, zaub mov science, thiab ib puag ncig tsom xam.

Nkag siab txog Rotovap

Qee lub sij hawm tsis ntev los no peb lis qhov chaw nyob ntawm tes, cia peb pib nrog kev teeb tsa kev nkag siab ntawm lub rotating evaporator. Ntawm nws qhov chaw, lub rotovap muaj xws li ib tug tig carafe, tsis tu ncua sov nyob rau hauv ib tug da dej da dej los yog roj da dej, ua ke nrog lub tshuab nqus tsev moj khaum. Qhov kev sib xyaw ua ke no tso cai rau kom nrawm nrawm ntawm cov kuab tshuaj ntawm qhov ntsuas kub qis dua li cov tswv yim zoo sib xws, txo qis kev noj nyiaj txiag sov ntawm cov khoom sib xyaw.

Cov Cai Ua Haujlwm

Evaporation

Cov qauv yog muab tso rau hauv lub hwj rotating, uas yog tom qab ntawd txo qis rau hauv dej los yog roj da dej. Kev sib hloov tsim ib zaj duab xis nyias ntawm cov kua rau ntawm lub raj mis sab hauv, ua rau thaj tsam ntawm evaporation.

Txo siab

Lub tshuab nqus tsev ua kom qis qis hauv lub cev, txo qhov kub ntawm qhov hnyav. Qhov no tso cai rau cov kuab tshuaj kom evaporate ntawm qhov kub thiab txias, txo qhov kev pheej hmoo ntawm thermal degradation ntawm tshav kub-sensitive compounds.

Condensation

Cov kuab tshuaj vaporized mus los ntawm lub condenser, qhov twg nws yog txias thiab condensed rov qab mus rau hauv cov kua daim ntawv. Cov kuab tshuaj condensed drips rau hauv lub ntim ntim rau tom qab siv lossis pov tseg.

Tswj

Tsis muaj xws li qhov kub thiab txias, siab, thiab kev sib hloov ceev yog saib xyuas thiab kho raws li qhov xav tau los ua kom zoo tshaj qhov tshem tawm cov kuab tshuaj thiab cov concentration.

Cov txheej txheem evaporation

Cov txheej txheem evaporation hauv ibrotary evaporatoryog predicated rau cov hauv paus ntsiab lus ntawm lub tshuab nqus tsev distillation. Los ntawm kev txo lub siab nyob rau hauv lub system, lub boiling point ntawm cov kuab tshuaj txo, yooj yim vaporization ntawm qis kub. Raws li lub hwj rotates, ib tug nyias zaj duab xis ntawm cov kua ntaub ntawv nyob rau hauv nws puab nto, maximizing deg cheeb tsam rau evaporation. Thaum tshav kub kub los ntawm ib puag ncig da dej accelerates tus txheej txheem no, zoo tshem tawm cov kuab tshuaj molecules los ntawm cov tshuaj.

Cov ntawv thov hauv Laboratory

Lub versatility ntawm lub rotovap ua rau nws indispensable nyob rau hauv ib tug myriad ntawm kev sim daim ntaub ntawv. Los ntawm qhov concentration ntawm cov tshuaj tiv thaiv sib tov mus rau kev sib cais ntawm cov tshuaj volatile, nws cov nqi hluav taws xob paub tsis muaj kev cia siab. Nyob rau hauv cov organic synthesis, piv txwv li, cov rotovap pab nyob rau hauv lub purification ntawm crude khoom, expediting tus txheej txheem ntawm hnyav tshem tawm kom yields ntshiab tshuaj. Ib yam li ntawd, nyob rau hauv lub cheeb tsam ntawm natural product extraction, nws ua hauj lwm pab raws li ib tug tseem ceeb lub cuab tam rau cais cov roj yam tseem ceeb thiab aromatic tebchaw los ntawm cov khoom cog.

Kev txwv thiab kev txiav txim siab

Thaum lub rotovap ua tau zoo nyob rau hauv nws lub peev xwm los evaporate ntau yam ntawm cov kuab tshuaj, suav nrog cov uas muaj cov ntsiab lus kub kub, nws cov txiaj ntsig zoo nrog cov dej pov thawj ze dua. Vim muaj cov yam ntxwv tshwj xeeb ntawm cov dej, uas yog nws cov cua kub ntawm vaporization thiab muaj zog hydrogen bonding, cov txheej txheem rotary evaporation yuav ua pov thawj tsawg dua. Tsis tas li ntawd, lub xub ntiag ntawm cov dej vapor seem hauv lub tshuab nqus tsev tuaj yeem cuam tshuam qhov kev ua haujlwm ntawm cov kuab tshuaj tshem tawm, yuav tsum tau ua tib zoo saib xyuas lub tshuab nqus tsev zoo thiab kev ua haujlwm zoo.

Dej evaporation: Ua tau thiab kev nyuaj

Hais txog qhov tseem ceeb ntawm peb qhov kev nug, rotovap puas tuaj yeem ua rau dej ntws zoo? Cov lus teb, luv luv, yog yog, txawm hais tias muaj qee qhov caveats. Thaum cov dej kub kub ua rau muaj kev sib tw, tshwj xeeb tshaj yog thaum piv rau ntau cov kuab tshuaj tsis haum, xws li ethanol lossis dichloromethane, nws muaj peev xwm tshem tawm cov dej los ntawm kev siv cov tshuaj tua kab mob.rotary evaporator. Txawm li cas los xij, kev ua tiav cov dej evaporation sai thiab muaj txiaj ntsig yuav tsum tau ua tib zoo ua kom zoo dua ntawm kev ua haujlwm tsis zoo, suav nrog qhov kub, lub tshuab nqus tsev, thiab kev sib hloov ceev.

Optimizing Parameters rau dej evaporation

Txhawm rau txhim kho kev ua haujlwm ntawm cov dej evaporation, ntau lub tswv yim tuaj yeem ua haujlwm. Ua ntej, nce qhov kub ntawm cov cua sov da dej tuaj yeem ua kom cov txheej txheem los ntawm kev muab lub zog ntxiv kom kov yeej cov dej kub ntawm vaporization. Txawm li cas los xij, kev ceev faj yuav tsum tau siv los tiv thaiv thermal degradation ntawm tshav kub-sensitive compounds. Thib ob, ua kom lub tshuab nqus tsev zoo tshaj plaws nyob rau hauv lub cev txhawb kev tshem tawm cov kuab tshuaj sai dua los ntawm kev txo qhov kub ntawm cov dej. Thaum kawg, kho qhov kev sib hloov ceev ntawm lub hwj tuaj yeem ua kom zoo dua qhov chaw ntawm qhov chaw raug, ua kom yooj yim dua evaporation kinetics.

Cov kev xav zoo thiab cov kev coj ua zoo tshaj plaws

Hauv kev xyaum, kev ua tiav dej evaporation siv arotary evaporatoryuav tsum ua raws li cov kev coj ua zoo tshaj plaws thiab ua tib zoo saib xyuas kom meej. Kev sib khi zoo ntawm qhov system yog qhov tseem ceeb los tiv thaiv cov pa tawm thiab tswj lub tshuab nqus tsev. Tsis tas li ntawd, preheating cov dej da dej kom ze rau qhov kub kub ua ntej pib evaporation tuaj yeem ua kom cov txheej txheem, txo cov sij hawm evaporation tag nrho. Kev tu thiab tu cov cuab yeej tsis tu ncua kuj ua lub luag haujlwm tseem ceeb hauv kev ua kom pom kev ua haujlwm zoo thiab ua haujlwm ntev.

Xaus

Hauv kev xaus, thaum lubrotary evaporatortej zaum yuav ntsib cov teeb meem thaum ua hauj lwm nrog evaporating dej, nws versatility thiab adaptability ua rau nws muaj peev xwm ua kom tiav qhov feat nrog ceev faj optimization thiab ua tib zoo saib kom meej. Los ntawm kev nkag siab txog cov hauv paus ntsiab lus ntawm lub tshuab nqus tsev distillation thiab siv cov tswv yim tsim nyog, cov kws tshawb fawb tuaj yeem siv lub zog ntawm rotovap kom tshem tawm cov dej zoo thiab ua rau lawv txoj kev sim siab.

Cov ntaub ntawv

Duan, Z., Jiang, L., Mao, L. (2019). Rotary Evaporation thiab nws cov evaporation Efficiency. ChemistrySelect, 4(16), 4755-4761. https://doi.org/10.1002/slct.201900515

Zhou, Y., Zhang, Z., & Zhu, L. (2020). Kev nce qib tsis ntev los no thiab kev cia siab yav tom ntej ntawm rotary evaporation hauv cov ntawv thov kev sim. Phau ntawv Journal of Chemical Engineering of Japan, 53(3), 192-199. https://doi.org/10.1252/jcej.19we215