Kev ntsuas roj ntsha tsib tog fermenter

Lub tswv yim ntawm roj ntsha fermenters tau hloov pauv ntau vim lawv pib. Cov qauv thaum ntxov muaj feem ntau yog ua rau microbial fermentation, qhov uas cov kab mob me tau muab cob rau hauv lub tank reactor. Sij hawm dhau los, lub lag luam pom ntawm ntau hom fermenters, suav nrog kev yoj sib xyaw, stirred-tank, thiab orbital shaken systems. Txhua yam ntawm cov hom no mus rau hom kev sib txawv ntawm tes ntawm cov xovtooj thiab ua haujlwm, muaj kev cuam tshuam txog kev sib txawv thiab kev nyuaj ntawm kev tsim tawm biophartutical.

Wave-sib xyaw fermenters, piv txwv li, tau pom cov ntawv thov thoob plaws hauv cov noob hlwb thiab kev cog qoob loo ntawm shear-rhiab cov kaus mom cov kaus mom. Lawv maj mixing kev ua minimizes ntawm tes puas, txhawb nqa kev noj qab haus huv ntawm tes thiab cov khoom lag luam siab dua. Nyob rau hauv kev sib piv, orbital shaken systems, txawm hais tias feem tsawg qeeb hauv kev loj hlob, feem ntau yog siv rau kev coj noj coj ua thiab cog cov pa roj oxygen. Cov kab ke no yog feem ntau ua rau cov ntawv thov kev kuaj ntsuas-ntsuas, ua haujlwm raws li kev tshawb fawb tseem ceeb rau kev tshawb fawb thiab theem pib.

Fermeration Chamber: Nov yog qhov tseem ceeb tshaj plaws uas qhov twg yog cov txheej txheem kev lom zem tshwm sim. Nws feem ntau yog ua los ntawm stainless hlau kom ntseeg tau tias detability thiab menyuam tsis taus.

◆ agitation system: Txhawm rau kom muaj kev sib xyaw ua ke thiab aeration sib xyaw ua ke nyob rau hauv fermentation chamber, agitators xws li impellers lossis stirrers ua hauj lwm. Cov kev pab no hauv kev tswj cov homogeneous thoob plaws hauv cov txheej txheem fermentation.

◆ Kev Rho Tawm Nruab Nrab: Cov khoom ntawm cov pa yog qhov tseem ceeb rau kev muaj kab mob aerobic. Qhov no tau ua tiav los ntawm cov spargers lossis huab cua diffusers uas ua kom paub txog huab cua rau hauv fermentation broth.

◆ Qhov System Txias: Kev tswj kom kub yog tswj xyuas kub yog tswj xyuas siv jackets lossis coils tau sau nrog lub txias. Qhov no tiv thaiv overheating thiab ua kom pom kev zoo hlob ntawm kev loj hlob.

◆ Ph Phaj Tswj Xyuas: Cov ph ntawm fermentation broth yog tshuaj xyuas thiab kho kom haum siv cov kua qaub, hauv paus, lossis cov buffers kom muaj ntau yam xav tau.

◆ Cov as-asfient feed ◆ pub mis: Cov khoom siv tswj tau ntawm cov as-ham, xws li suab thaj, amino acids, cov vitamins, thiab cov minerals, yog muab kom txhawb nqa kev loj hlob ntawm tes thiab metabolism.

Cov versatility ntawm biological fermenters ua rau lawv indispensable nyob rau hauv ntau theem ntawm kev tsim biophartutical. Ib qho ntawm cov ntawv tshaj tawm tseem ceeb tshaj plaws yog kev tsim cov tshuaj muaj cov tshuaj pleev cov roj ntsha uas siv cov ntawv Mammalian. Tsis zoo li microbial hlwb tuaj yeem tsim cov protein ntau dua nrog cov khoom siv ua ke tom qab, ua rau lawv muaj cov proteutic, ua rau lawv cov protein ntau.

Transgenic cov tsiaj, tshwj xeeb yog transgenic tshis thiab luav, tau tawm raws li muaj cov qauv cuam tshuam rau kev tsim cov tshuaj pleev cov protein. Los ntawm kev sib xyaw ua ke tib neeg cov noob caj noob ces cov khoom siv tau tsim cov tsiaj txhu hauv lawv cov mis lossis lwm yam mis. Qhov kev mus ze no, hu ua "kev ua liaj ua teb molecular," muaj ntau qhov zoo, suav nrog cov nqi ntau dua, muaj ntau dua qoob loo, thiab txhim kho kev nyab xeeb kev nyab xeeb profiles.

Piv txwv li, Arytryn, ib lub antombinter acthatrombin antithrombin antithrombin tshuaj tiv thaiv kev pom zoo los ntawm FDA hauv xyoo 2009, yog tsim nyob rau hauv cov mis nyuj ntawm transgenic tshis. Ib yam li ntawd, cov roj Ruconest, ib tug neeg ua haujlwm ntawm cov neeg hauv cov neeg hauv cov mis mos hauv cov mis nyuj ntawm transgenic luav. Cov khoom lag luam no ua rau cov khoom siv tau thiab ua tau zoo ntawm Transgenic Tsiaj Reactors hauv kev tsim bioophartutical.

◆ Kev nce qib hauv cell kab lis kev cai tshuab: Kev txhim kho ntawm cov tshiab cell kev cai xov xwm tshaj tawm, pub cov tswv yim, thiab cov qauv tshuaj zoo tagnrho tau txhim kho cov khoom lag luam ntawm tsiaj. Cov kev txhawb nqa no tau qhib qhov kev tsim cov khoom muaj cov protein thiab cov tshuaj tiv thaiv, txo tus nqi thiab muaj cov khoom muaj ntawm cov khoom lag luam no.

◆ Kev tsim kho hauv Bioractor tsim: Tshiab Biotactor tsim, xws li nthwv-sib xyaw thiab nce qib shaken ntawm cov khoom lag luam thiab huab hwm coj ntawm cov khoom lag luam rhiab thiab ntau lawm cov khoom lag luam zoo. Ib qho ntxiv, kev siv ntawm Biineactors pov tseg tau txo cov kev pheej hmoo tsis huv thiab yooj yim ua haujlwm yooj yim.

◆ Kev koom siab ntawm Biroccess automation: Kev sib xyaw ua ke ntawm kev siv tshuab thiab tswj cov txheej txheem tau txhim kho cov txheej txheem depeathabs, txo cov neeg tsav tsheb yuam kev, thiab tswj hwm ntawm cov txheej txheem tseem ceeb. Qhov no tau coj coj mus ntxiv cov khoom lag luam, txo qis qis, thiab cov khoom lag luam zoo.

Kev Txiaj Ntsim Kev Nyab Xeeb thiab ib puag ncig ib puag ncig: Biotechnology kev lag luam tau tsom mus rau txo nws txoj kev cuam tshuam ib puag ncig thiab txhim kho kev ua kom ruaj khov. Qhov no tau coj mus rau kev txhim kho bioprocesses tshiab uas siv cov peev txheej txuas ntxiv dua tshiab, thiab txo qis kev siv zog. Ib qho ntxiv, kev siv ntawm ib leeg-siv cov bioractors tau txo qhov xav tau kev tu thiab kom tsis muaj menyuam, ntxiv txo kev cuam tshuam ib puag ncig ib puag ncig.